Overview The Applied Software Systems Laboratory (TASSL) is a interdisciplinary research center that complements the NSF Cloud and Autonomic Computing Center (CAC), and is part of Department of Electrical and Computing Engineering and the School of Engineering at Rutgers University. TASSL overarching missions is to develop conceptual models and implementation frameworks, based on the theoretical foundations of high performance, distributed systems and networking, for solving real-world problems on very large and pervasive distributed systems such as the national hybrid cyberinfrastructure. Designing, developing and deploying advanced software systems is an integral part of the TASSL mission and TASSL researchers have deployed software systems such DataSpaces/DART, GrACE/MACE, CometCloud, Accord, Squid, Meteor, etc. The Cloud and Autonomic Computing Center (CAC), an NSF Research Center funded by the I/UCRC program, combines resources from universities, private companies, and the federal government to conduct fundamental research on making all kinds of computer systems and applications - from humble desktop computers to air traffic control systems - more reliable, more secure, and more efficient. They provide opportunities for multidisciplinary problem solving. They fosters collaborations with scientists and engineers from applied disciplines and provided students with the opportunity to interact with the researchers from varied disciplines and to collaborate with then to solve real-world problems. Research activities are focused in the broad area of parallel and distributed computing and include programming and runtime systems, autonomic computing, scientific computing and software engineering.